Every FDA-Approved Presbyopia Eye Drop Explained
Four prescription products are FDA-approved to treat presbyopia in adults. Compare their active ingredients, labeled dosing, and warnings—without treating separate clinical trials as a head-to-head ranking.
Educational information only. An eye-care professional must determine whether any prescription medicine is appropriate for you.
The four U.S.-approved products
Approval dates and dosing below come from FDA approval materials and prescribing information current at the time of this review.
| Product | Active ingredient | Initial FDA approval | Labeled dosing overview | Source |
|---|---|---|---|---|
| Vuity | Pilocarpine HCl 1.25% | October 2021 | Once daily; the current label permits a second dose 3–6 hours later. | FDA label |
| Qlosi | Pilocarpine HCl 0.4% | October 2023 | Once daily or as needed; a second dose may be used 2–3 hours later, up to twice daily. | FDA label |
| VIZZ | Aceclidine 1.44% | July 2025 | Two drops in each eye, separated by two minutes, once daily. | FDA label |
| Yuvezzi | Carbachol 2.75% / brimonidine tartrate 0.1% | January 2026 | One drop in each eye once daily. | FDA label |
How these drops work
They use pupil constriction to create a pinhole effect that increases depth of focus. They do not restore flexibility to the aging lens or reverse presbyopia.
Why trial percentages are not a ranking
Separate trials can use different participants, comparators, dosing, lighting, time points, and endpoints. A larger number on one product page does not by itself prove that product is better for an individual patient.
Warnings matter
Miotic labels include warnings about blurred or dim vision and retinal tear or detachment. Do not drive if vision is unclear, and seek urgent care for sudden flashes, floaters, or vision loss.
Review the label warnings →Cost and availability change
Verify current cash price, insurance coverage, pharmacy availability, and manufacturer programs at the time you consider filling a prescription.
Visual training is a different category
Get Visionary is a wellness app with guided exercises for detail, contrast, recognition, and visual speed. It is not a prescription treatment, does not change the eye's lens, and does not replace glasses or professional eye care.
Prepare for an eye-care appointment
Organize questions about your eye history, driving, lighting, other medicines, and the current label warnings. The guide never recommends a product.
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